Skip to main content
2024 47th International Conference on Telecommunications and Signal Processing (TSP)

Full Program »
Video (.mp4)
View File
mp4
43.3MB

Exploring Speech Profiles in Parkinson's Disease Patients on Long-Term Dopaminergic Medication

Hypokinetic dysarthria (HD), prevalent in Parkinson's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage, patients displayed three distinct speech profiles, one more severe regarding the number of HD domains affected. Patients with this profile were associated with slightly longer recorded PD duration. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. However, as in subtypes, no differences in clinical scores were observed between profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Daniel Kovac
Brno University of Technology
Czechia

Krystof Novotny
Brno University of Technology
Czechia

Jiri Mekyska
Brno University of Technology
Czechia

Lubos Brabenec
Masaryk University
Czechia

Milena Kostalova
Faculty Hospital and Masaryk University
Czechia

Irena Rektorova
Masaryk University
Czechia

 

Privacy Policy

Powered by OpenConf®
Copyright ©2002-2024 Zakon Group LLC